KETOMED 10%
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Composition
Each 1 ml contains:
Ketoprofen base 100 mg
Properties
Ketoprofen is a derivative of phenylpropionic acid, and belongs to the non-steroidal anti-inflammatory drugs. Like all such substances, its principal pharmacological actions are anti-inflammatory, analgesic and anti-pyretic. The mechanism of action is related to the ability of ketoprofen to interfere with the synthesis of prostaglandins from precursors such as arachidonic acid.
Indications
For Horse, Cattle, Pig, Dogs & Cats:
Horse:
The alleviation of inflammation and pain associated with musculoskeletal disorders.
The alleviation of visceral pain associated with colic.
Cattle:
The supportive treatment of parturient paresis associated with calving.
Reducing the pyrexia and distress associated with bacterial respiratory disease when used in conjunction with antimicrobial therapy as appropriate.
Improving the recovery rate in acute clinical mastitis, including acute endotoxin mastitis, caused by Gramnegative micro-organisms, in conjunction with antimicrobial therapy.
Reducing oedema of the udder associated with calving.
Pigs:
Reducing the pyrexia and respiratory rate associated with bacterial or viral respiratory disease when used in conjunction with antimicrobial therapy as appropriate.
The supportive treatment of Mastitis Metritis Agalactia Syndrome in sows, in conjunction with antimicrobial therapy as appropriate.
Dogs & Cats:
Inflammation and pain associated with musculoskeletal disorders.
Target species
Horse, Cattle, Pig, Dogs & Cats
Dosage instructions
Horse:
By Intravenous administration.
For use in musculo-skeletal conditions: 1 ml of KETOMED 10% / 45 kg body weight, once daily for up to 3 to 5 days.
For use in equine colic: 1 ml of KETOMED 10% / 45 kg body weight given by intravenous injection for immediate effect, a second injection may be given if colic recurs.
Cattle:
By Intravenous or intramuscular administration: 3 ml of KETOMED 10% / 100 kg body weight, once daily for up to 3 days.
Pigs :
By Intramuscular administration: 1 ml of KETOMED 10%/33 kg body weight.
Dogs:
By subcutaneous, intramuscular or intravenous injection: 0.2 ml of product per 10 kg once daily for up to 3 days.
Cats :
By subcutaneous injection: 0.2 ml of product per 10 kg once daily for up to 3 days.
By mouth: 0.1 ml of KETOMED 10% / 10 kg once daily for up to 5 days.
Warnings & Precautions
The use of ketoprofen is not recommended in foals under the age of 15 days. Use in any animal less than 6 weeks of age or in aged animals may involve additional risk. If such use cannot be avoided animals may require a reduced dosage and careful management.
Avoid use in any dehydrated, hypovolaemic or hypotensive animals as there is a potential risk of increased renal toxicity.
Avoid intra-arterial injection.
Do not exceed the stated dose or duration of treatment.
Contra Indications
Do not administer with other non-steroidal anti-inflammatory drugs (NSAIDs) concurrently or within 24 hours of each other, corticosteroids, diuretics or anticoagulants.
Some NSAIDs may be highly bound to plasma proteins and compete with other highly bound drugs which can lead to toxic effects.
Concurrent administration with nephrotoxic drugs should be avoided.
Do not use in newborn domestic animals due to presence of benzyl alcohol in product as preservative.
Side Effects
In very rare cases, due to the action of inhibition of prostaglandin synthesis, there can be the possibility in certain individuals of gastric or renal intolerance.
In very rare cases allergic reactions may occur.
Withdrawal time
Cattle:
Meat and offal:
following intravenous administration: 1 day
following intramuscular administration: 2 days
Milk: zero hours
Horses:
Meat and offal: 1 day
Milk: Not authorized for use in lactating animals producing milk for human consumption
Pigs:
Meat and offal: 2 days
Storage condition:
Store at temperature not exceeding 30°C and used after opening for 50 days at temperature not exceeding 30 °C
Packaging
Glass vials :10, 30, 50, 100, 200, 250 &500 ml
